Related Topics: Features, HRT, Menopause, Osteoporosis

How to come off Hormone Replacement Therapy

If HRT is stopped suddenly the oestrogen levels will quickly drop to very low levels. This may not produce any symptoms at all, but in many women it causes most of the symptoms associated with the menopause to appear.

Dame Dr Shirley Bond

After trying HRT for a few months, or longer, many women wish to come off it due to side effects.  However, stopping HRT is not as easy as starting it.

If you want to stop your HRT you should always talk to your doctor first.

Having made the decision, you can if you wish just stop it – but this is not advisable.  Stopping suddenly can produce quite severe symptoms and it is better to wean yourself off the HRT over a period of time.

What’s Involved

When you are taking HRT you are artificially increasing your levels of oestrogen and, with traditional HRT, this may or may not be combined with a chemical progestogen to protect the uterus.

It is often thought that after the menopause women no longer make any oestrogen, but this is not true.  Another false belief is that women without ovaries do not make any oestrogen.

It should be remembered that women produce three different types of oestrogen: Oestradiol, Oestrone and Oestriol.  In a woman’s reproductive years most of her oestrogens are made in the ovaries and the main oestrogen is the strong oestradiol. After the menopause, a woman’s oestrogens are made in muscle and fatty tissue by the conversion of another hormone androstenediol into oestriol.  The amount of oestradiol produced at this time is very low.

The levels of oestrogen, usually oestradiol, in a woman taking HRT will be as high, or even higher, than the levels found in younger women. Certainly the levels will be much higher than would be normal.

If HRT is stopped suddenly the oestrogen levels will quickly drop to very low levels. This may not produce any symptoms at all, but in many women it causes most of the symptoms associated with the menopause to appear. These symptoms are sometimes more severe than they were before starting the HRT.

How To Come Off HRT

The best way to come off HRT is to do it slowly. The ways in which you do this will to some extent depend on the sort of HRT you are taking and the following are some suggestions:.


This will depend on whether your tablets are designed to produce a monthly bleed, which most women prefer, or not.

If you are having a monthly bleed then if the oestrogen tablets can be cut in half, or smaller, you can reduce the amount of oestrogen you are taking by doing this. It is always better to take a lower daily dose than to take the daily dose on alternate days. The progestogen should be kept at the same dosage.

You may find that when you reduce the oestrogen you do not experience a bleed in the usual way. This is not a cause for concern and is because the lower level of oestrogen has not built up such a thick lining to the uterus and it does not need to be shed.  Eventually you will reach a very low level of oestrogen and you can then try stopping completely and evaluate how you are.

If the tablets cannot be cut into smaller pieces then try taking the oestrogen on alternate days. The progestogen should be taken every day as before. You may find that you do not have a period but this is not important. When you find that you are taking only one or two oestrogen tablets a week then you can stop.

If you are taking a continuous combined oestrogen and progestogen tablet then you are probably not having  a monthly bleed. To reduce your dosage, try cutting the tablets in half. If this is not possible then take the tablets every other day and then every third day and increase the number of days between until you find that you can manage without them.


These have become quite popular over the past few years but it is more difficult to reduce the dosage you receive and it will depend upon your type of patch.

It is important to remember that a patch is designed to contain an amount of oestrogen to be absorbed over the period of time that you are instructed to leave the patch in place. If you leave it on longer you will not be getting less oestrogen. You will not be getting any oestrogen at all. Some people do reduce their patches like this but there are better ways.

There are two ways in which the oestrogen and progestogen can be administered by patch. One has oestrogen patches and is combined with tablets of progestogen taken for 12 days each cycle. The other type has both oestrogen and progestogen in patch form. There are usually patches just containing oestrogen for the first part of the cycle and then patches containing both hormones for the later part of the cycle.

Look carefully at your patch. There are two main styles: one is called a matrix patch and is very flat, and the other seems to have liquid or gel in it.

If you have matrix patches it is very easy to reduce the amount of oestrogen you take each day. Cutting slices off the patch and gradually reducing it can do this. You should continue to take your progestogen tablets or the progestogen part of your patch as usual.  As with the tablets, as you reduce your oestrogen intake you may find that you no longer have a bleed if you have been experiencing one on your particular patch.

If your patches have gel in them you cannot cut them in half. The best way to reduce the amount of oestrogen that you absorb from the patch each day is to reduce the surface area of the patch.  You can do this by sticking a small piece of waterproof sticking plaster over an area of the absorbing surface that goes next to your skin. You can then leave the patch on for an extra day because the oestrogen in the patch will take longer to absorb because you have reduced the area over which it is absorbed. You then increase the size of your piece of sticking plaster and leave the patch on longer and longer. Then eventually you will no longer use it at all.

If you have had a hysterectomy and as a result are taking oestrogen on its own then you can reduce your oestrogen in the ways described above, forgetting about the progestogen.

The speed at which you reduce your oestrogen is entirely up to you and you will be guided by how you feel.

When you decide to stop your HRT there are certain things you should do.

First, do start to take a supplement specifically designed for dealing with the menopause. There are a number of these on the market and you should be able to obtain advice in a health store or Chemists.

Next, if you have been advised to take HRT for osteoporosis, or indeed if you have been on HRT for several years, it is important that you have a Bone Mineral Density Screening. The reason for this is that the oestrogens in HRT do not build up new bone but stop bone from breaking down. The oestrogens can only do this while you take them. The problem that can then arise is that when you stop taking the HRT then the old bone that you have retained will start to break down.

To sum up: in order to help your bones at this time it is essential to take the correct supplement for your bone health, exercise in order to build up new bone, and consider using natural progesterone to help you to build up new bone.

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New comments are now closed on this article
Comments 209
Sorted by:  Date | Recommended
AnnA Rushton | 5:20 pm, April 22nd, 2018

Unfortunately if you suddenly stop oestrogen after long-term use you will get these side effects. It is best to wean yourself off it slowly and supported by bioidentical hormones at the same time.This article by Dr Tony Coope will be helpful.

Charyle | 1:32 pm, April 21st, 2018

I have been taking estradiol .50 mg for almost thirty years. I want to stop! A few years back I totally stopped and within days I found myself being confused and forgetful, so I started taking them again. About a week ago I stared taking one every other day. Now I feel sort of dizzy and slight headaches. Can you help me? Please!!!

AnnA Rushton | 4:00 pm, April 1st, 2018

Depends on the dosage and type Becky but usually fairly quick which is when the withdrawal symptoms often kick in.

Becky Hosey | 4:46 pm, March 31st, 2018

How long does it take oral estrogen to leave your system? I had a total hysterectomy and BSO 12 years ago at the age of 31. Will the oral estradiol stay in my system for a while if I stop it or will the levels drop and leave my system immediately?

Thank you

Janet | 12:56 am, March 30th, 2018

Im 55 years old.
I’m taking premia 5 continuous pills. I’m currently taking on alternate days. When I get to taking on every 3rd day, should I incorporate a herbal supplement such as Femula on the other 2 days? And thus gradually less Premia many weeks or months can I expect this process to take roughly? Thank you

AnnA Rushton | 8:26 am, February 28th, 2018

Lauren Please email for individual help with your symptoms and how to safely come off HRT as clearly you are not responding well and supplementing with bioidentical hormones can help your hair loss.

Lauren | 7:42 am, February 27th, 2018

I am only 38 but have been on hrt since August last year. My hair has been falling out quite a lot to the point it is going thin & I had lovely thick hair before. I am on angelic & have been since January. I was on elleste duo before but wanted to change due to my hair. I have been on my period for 2 weeks now & have started having restless sleep. I want to come off but scared my hair will come out even more or other things will worsen.
I’d like to try natural remedies as on lots of supliments to help my hair & really don’t want to be on hrt

AnnA Rushton | 12:41 pm, January 20th, 2018

Nerine if you come off when supported by bioidentical hormones then your symptoms will not go into withdrawal from the HRT in the way they do when you try to cut down or stop on your own. Use Serenity alongside your Estradot and not attempt to cut down except as advised in Dr Coope’s article.

Nerine Gargiulo | 10:56 am, January 20th, 2018

Hi I had a full hysterectomy was on Premarin 625 for like 15 yrs now on Estradot 25 for about 7 years I am 72 so desperately will like to stop as I get very bad headaches and live on syndols it’s easy for people to say stop I have a half plaster on now but I get bad hot flushes and I am a hot person really need some advise thank you

AnnA Rushton | 7:19 pm, January 16th, 2018

You are unlikely to be able to stay on Progynova for ever Julie as your doctor has suggested, however the key is to come off very slowly as recommended by Dr Coope in the article. A couple of weeks is simply not long enough and it needs to be done only when supported by bioidentical hormones to replace the HRT.

Julie | 2:42 pm, January 16th, 2018

I have been taking Progynova (oestradiol 1mg) for 11 years to control menopausal symptoms. My GP suggested I wean off it, which I did over a couple of weeks. However, I ended up with unmanageable and unbearable insomnia, which I struggled with for around 8 weeks, before I recommended Progynova in frustration. The insomnia disappeared after around 7-10 days. I don’t know if it was in fact ceasing the Progynova that caused the insomnia or the fact that I commenced Vitamin D at the same time as weaning off Progynova. I stopped the Vit D and recommenced the Progynova at the same time, so I’m unsure which was the problem. I’d like to come off Progynova, as I’ve been on it so long, but I’m terrified of getting insomnia again.

AnnA Rushton | 11:15 pm, January 8th, 2018

You must discuss this with your doctor or compounding pharmacy Marilyn as these are types of hormone we are not familiar with.

Marilyn Johnson | 5:10 pm, January 8th, 2018

Lyn, I have Biote pellets in my hip. Two months now plus Projest 225 compounded capsules and I hydroids. I want off everything. Did you have pellets? Think I can just stop?.

AnnA Rushton | 11:55 am, December 12th, 2017

Karen Kliogest contains both oestrogen and a synthetic progestin both of which have side effects associated with bloating. If you wish to naturally replace both hormones then 20-1, which is a combination cream with the majority ingredient of bioidentical progesterone plus a small amount of two natural oestrogens in a well-balanced formula, would be what we would suggest, but you do need to discuss this with your doctor.

Karen | 8:15 am, December 12th, 2017

I have just started taking Kliogest 2mg+1mg. I have been on it for only 4 days & now I’m sore, bloated & my stomach feels like period pains when I pee, otherwise I feel ok. I’ve now been told to try every second day & see how it goes.
The reason for me taking hrt is my pituitary gland is gone so I don’t produce any hormones at all. I take a variety of medication but would like to know if any of you have been through my Kliogest symptoms.
Thanks in advance

Karen | 8:09 am, December 12th, 2017

I have just started taking Kliogest 2mg+1mg. I have been on it for only 4 days & now I’m sore, bloated & my stomach feels like period pains when I pee, otherwise I feel ok. I’ve now been told to try every second day & see how it goes.
The reason for me taking hrt is my pituitary gland is gone so I don’t produce any hormones at all. I take a variety of medication but would like to know if any of you have been through my Kliogest symptoms.
Thanks in advance

AnnA Rushton | 10:37 am, November 20th, 2017

Corinn we do not have an oral progesterone as it has to be in a high dose to be processed through the liver so you need to discuss this with your doctor.

Star | 10:07 pm, November 19th, 2017

I am dizzy too, I was on bio pellets with oral bio progesterone 2 years then Had hysterectomy 4 weeks ago. Doc put me on oral Estradial and I am having severe bowel pains. Back pounding anxiety can’t sleep. Help! Would oral bio progesterone be ok at 200mg?

Sriasti | 7:33 pm, November 15th, 2017

Hi Deanna
You still seem young to get off HRT. Thats what i have been advised. Are you perhaps going to the natural route?

AnnA Rushton | 1:08 pm, October 12th, 2017

Darla we are unable to reply here as this does require input from a medical doctor so please make that appointment as soon as possible to be checked out as a number of things could be causing this problem.

Darla Gill | 9:26 pm, October 10th, 2017

Hi, this is kind of long but I really Need Help if someone wouldn’t mind taking the time. I am desperately wondering if anyone else has suffered from extreme lethargy either on or coming off the estradiol patch. I’m 46, 5’2 bout 136 lbs and had to have a complete hysterectomy almost 3 years ago. I finally got comfortable on this patch after trying other things about 7-8 months after my surgery and was just taking it for hot flashes and the fear that I needed those hormones back in my body for my mood, sex life… Etc. I felt fine and still feel fine as far as mood and hot flashes(NONE)-although I’ve noticed my sex drive isn’t exactly what it used to be. I should say I’ve been on Lexapro 25 mg for about 6 yrs. My Gyn and Fam Pract was/is aware-no problems w/it.
My hysterectomy was bad as my insides were mixed up, adhered to each other/my inner walls, so I was down awhile and just seemed to never fully get my energy back. I eventually went back to walking again(bad back so bout all I can do) got a pack of daily multivitamins for women the salesperson in GNC recommended and just tried to get back to my life and put that feeling of something not being exactly right in the back of my mind. But, it’s gotten horrible in the last 6-7 months. It feels like something heavy running thru me and all I want to do is sit. I don’t feel like me anymore. My house doesn’t get cleaned, My 16 yr old son comes in from baseball practice and if his Dad, my husband is off-shore, he has to eat a tv dinner cause I’m too tired to cook. I can’t remember things and I’m feeling confused a lot. I decided before I went to the Doctor because…. Which Doc would I go to? I’d get off the patch and just see. So…instead of changing it when I was suppose to, I just left it on a little over a week, then took it off-3 days ago although it was prolly completely gone long b4, I don’t knw. Thing is, if possible…the extreme lethargy IS WORSE!! It’s like molten lava coursing thru my veins. Like a physical thing. I don’t knw whether to put a patch back on!(Kinda thinking about it)I just don’t knw. Anyone with any experience, help or suggestions-besides ONLY telling me to make a Drs. appt(that’s a given & I’m going to do that!!) PLEASE HELP! I feel like I’m going crazy here and while I’ve always been able to put any kind of depression on a back burner and be my happy-go-lucky self, this is making it VERY hard to even get out of bed in the morning and since I don’t work….I don’t have to!
Thanks in advance for any help!

AnnA Rushton | 6:09 pm, September 26th, 2017

Gabriele we cannot advise you on whether you should come off or not as you must discuss it with your doctor but such bloating is often related to the oestrogen content in HRT. 20-1, which is a combination cream with the majority ingredient of bioidentical progesterone plus a small amount of two natural oestrogens in a well-balanced formula, and what many women use instead of HRT.

Gabriele | 1:26 am, September 25th, 2017

Hi, I’ve been on femhrt for 6 days and my stomach is so bloated and hurts, and I chronically clear my throat and cough. It’s so bad I can barely eat. Should I stop the femhrt and if so how should I stop?

AnnA Rushton | 12:36 pm, September 2nd, 2017

Theresa without knowing what progesterone, or progestin, you were on we can’t answer that here. Please email for individual help with your symptoms.

Theresa | 10:25 pm, September 1st, 2017

Any idea of how much progesterone cream I should use. Serenity looks really good. So if I go off my progesterone can I start with a cream right after that?

AnnA Rushton | 9:12 am, August 25th, 2017

Louise we can’t answer in detail here so please send this information to who will be able to help you.

Louise caunt | 7:17 am, August 25th, 2017

Hi there.
I’ve been on Femoston tablet Hrt 2/10 higher dose for five years. I’d like to start to reduce in order to see whether I still need Hrt. I started peri menopause at age 44. Now 49. I tried doing the oestrogen every other day. I feel rubbish now at the end of this month. Tired and achey and moody. No energy. Occasional flushes. Help. All of this year, I’ve hardly had any monthly bleed at all. Should I change my Method? I’m told Femoston has the kinder hormones? When I first went on it, I felt amazing. However two years in, I was getting a lot of upper gastric pain and certainly have had bouts of lots of headaches.
Help !

AnnA Rushton | 9:16 am, August 22nd, 2017

Theresa oral progesterone is processed through the liver where much is lost so a cream formulation i more effective. Stress massively impacts your hormones as well and with all forms of HRT we recommend you come off slowly. Your symptoms indicate excess oestrogen and low progesterone so if you are coming off your current regime we suggest starting with a progesterone only cream such as Serenity. You may find this article helpful but for further information email

Theresa | 7:16 pm, August 21st, 2017

I started bio identical hormones almost 4 months ago. Oral progesterone 100 mg, estriol cream to the arms, testosterone to the labia along with nature thyroid. The first 2 months were good but the 3 month was ok then this month has been horrible. My doctor took me off testosterone and Dhea and put me on dim but I am having horrible headaches, fatigue. Muscle pain, can’t sleep and other problems. I want off of these things. I am going to see her on Wednesday and to see how I can get off of these things. I also lost my husband 6 months ago who was the love of my life. Do you think being on them only 4 months I will be able to get off them and feel human again? Any advice?

Nadine | 11:47 pm, August 17th, 2017

I was wondering if you had previously had a complete hysterectomy before starting Hrt? I was also wondering how old you are now? I’m 58 and had a complete hysterectomy about 18 years ago and I’m just weaning off. I’m down to half for the last three months. I’m always hot but but now I’m just not feeling myself, kind of shacky no energy. Was this like you?

AnnA Rushton | 12:47 pm, August 6th, 2017

Coming off HRT can bring on withdrawal Beth so best done slowly and under supervision. If your patches are oestrogen only then start by using Serenity at the same time as you gradually cut back and monitor your symptoms.

Lyn | 11:02 pm, August 5th, 2017

I too had a terrible time trying to get off the HRT also…I was on them for many years and like you kept going back on them because the hot flashes were horrible…You may want to try to wean off them but honestly if you can wait a few months the hot flashes do subside…I only get maybe 1 or 2 now and they are bearable…Sure beats getting breast cancer which is a whole different story…Good luck…Also try some natural drinks with apple cider vinegar…has helped me with other issues with going off HRT…and has lots of good benefits…After being on those hormones our bodies need to detox…

Beth | 10:04 pm, August 5th, 2017

I have also been on hrt for 7 yrs, I’m 59. i’ve been off hrt 3 weeks now, I’ve done 3 weeks twice before but can’t seem to get any further than that. I’m reading all these comments and am thinking maybe I should cut my patch in half and go back on, it’s getting unbearable with the flashes, it’s embarrassing especially at work! Any advice….. Beth

Deanna | 5:41 pm, August 4th, 2017

I went into full menopause at 28. Been on hrt 7 years…3weeks off.killing me.sweating no sleep…gunna push through

Lyn | 9:22 pm, August 2nd, 2017

I was hoping to at least help one person…I am happy to hear that you will be stopping them…yes they do make you feel great but could be a false sense of security in the long run…and side effects do not last that long when coming off…just eat healthy and exercise and that will help a lot…Wish someone had explained this all to me….stay blessed and be healthy…

Dee | 9:38 pm, July 31st, 2017

Thank you Lyn, I hope you are on the road to recovery. What a horrible shock that must have been for you. What you wrote here really had an impact on me.
I’ve been taking Premarin for 6 years and am about to try to come off it. I don’t have any health worries and feel happy and well on it but do worry about the increased risk of breast cancer.
I’m grateful to you for sharing your experience. Keep well x

AnnA Rushton | 9:31 am, July 21st, 2017

Linda it is never advisable to suddenly stop HRT and best if you support the process with Serenity bioidentical progesterone cream as it indicates in the article.

AnnA Rushton | 9:30 am, July 21st, 2017

Please read the article Janet where it tells you it is never advisable to suddenly stop HRT and best if you support the process with Serenity bioidentical progesterone cream.

Lyn | 2:44 pm, July 20th, 2017

I was on Premarin for about 20 years until I was diagnosed with Breast Cancer which I had no idea was caused by this HRT…I immediately got off and went right into menopause again with the hot flashes…but now after almost 6 months off of them I am feeling almost normal again and the hot flashes have subsided to almost none….If you are on Premarin I suggest you try to stop and just remember it is not worth the chance of getting breast cancer which is a nightmare….just remember that after a few months you will start to feel ok again once it is out of your system…thanks for reading this and hope it can help at least one person…also natural is the best way to go for you and your body….God Bless…

Linda | 3:34 pm, July 19th, 2017

Hi, i started taking livial a few month ago and i am thinking of stop taking it due to my finance. Is there any side effect n what should i do?

Janet gildon | 2:19 pm, July 19th, 2017

I had a hysterectomy at 27 only have my ovaries im now 53 and on everol 25mg patches twice a week but i have put on over a stone my belly looks huge and its depressing iv never had weight issues but boy o boy i do now i want to stop the patches does anyone know if its OK just to stop if not anyone got any advice please thanks

AnnA Rushton | 11:53 am, July 11th, 2017

Speak to your pharmacist, or whoever supplied them, as we have no information on this drug PJ.

PJ | 9:07 am, July 11th, 2017

Please could you tell me the half-life of Indivina 2.5 Tablets? I have been unable to find the information anywhere.
Many thanks.

neomi95 | 12:26 am, June 27th, 2017

I disagree.

AnnA Rushton | 8:57 am, April 30th, 2017

Tina the article does indicate how to cut down and come off oestrogen and if you have osteopenia you would also need progesterone, particularly if you intend staying on a low dose of oestrogen. There is no specific age recommendation that we are aware of but long term oestrogen use does carry health risks as your doctor has indicated. This article by Dame Dr Shirley Bond may also be helpful but if you need more help email

Tina | 2:15 pm, April 23rd, 2017

I have been on estrogen patch for 17
Years after having a complete hysterectomy.. I’m thin 115lbs And was told that I was not storing estrogen well I was put on two patches at the same time. and .05 I have weaned myself down over the years to .025what is the best way to come off of it I’m worried abt my state of mind as I’m
Already a little forgetful ang have a little
Osteopenia in my hips .my doctor said she likes all her patients to be off of estrogen when they are 60 years old there is a mixed data about it calling me a joke but there are other definite side effects that of been proven that the average age of 62 to 63 I will be 60 to September need to know what Avenue I need to come off of this estrogen with little or no repercussions thank you

AnnA Rushton | 6:40 pm, April 15th, 2017

The article indicates how best to do this. However all women do vary and it is impossible to say whether you will suffer side-effects from withdrawing from your HRT but is always best to do is supported by bio identical hormones? With such very long term use you should come off as slowly as possible and make sure you are on using the recommended double dose of power denticle Holman for at least the first month, if not longer.

Coleen Young | 7:27 pm, April 11th, 2017

I have been on Estrotest EEMT 1.25/2.5 MG tablets now for 20 years when I had a total hysterectomy. I want to wean myself from this. I started taking half each day now. How long should I do this, when can I stop completly and how severe of side effects will I experience?

AnnA Rushton | 11:10 am, March 15th, 2017

Corrinn we can’t comment on your troches as they vary so much in dosage so please speak to whoever prescribed them for you. However bioidentical cream hormones are normally in much lower doses so do not have side effects or withdrawal symptoms. With twice daily application as directed they are out of your system within 24 hours.

AnnA Rushton | 11:08 am, March 15th, 2017

Jane bioidentical hormones are out of the body within 24 hours when used in rotation as directed. However this is not the best place for questions as articles are not monitored daily so if you have future queries please email

Corrinn Cahoon-Neumann | 11:20 pm, March 14th, 2017

Hi, I also would like to know. I just got off bio identical hormones(given in troche form). I had been on them for just over a year. They definitely took away my hot flashes and I could sleep, however I kept feeling like I wad in a rocking boat everyday, and getting worse. On the advice of my medical doctor I weaned off. Now I am dizzy everyday, major hot flashes again and can’t sleep. Glad to not feel like I am in a rocking boat though. I also am wondering how long before it is out of my system, and could a person do a cleanse? I hope someone has an answer. I wish you luck.

Jane Strickland | 2:41 pm, March 14th, 2017

No one is answering my questions. How long does it take for hormone replacement therapy to leave the human body?i was on it for 2 mo. The cream and do not like it. I just wanted to know how long before its out of my body? Thanks

AnnA Rushton | 1:17 pm, February 12th, 2017

We cannot comment on the legality of your situation but your doctor is not alone in taking you off HRT due to the health risks. If you are concerned about osteoporosis then supplemental bioidentical progesterone is the best hormone to help with this as Dr Bond explains in this article.

Miriam | 11:45 am, February 12th, 2017

After 19 tears tibolone my doctors are refusing to prescribe it because im 72. Iwas given it 3 months ago. I was put on it for osteoporosis and am now worried. I missed one as instructed and took one next day but feel so ill and down . I have stomach ache backache and cant eat and want to be sick. Have i got any legal right or choice to stay on them. I have felt young on them most of the time and want to remain on them. Look forward to early reply. Thanks.

AnnA Rushton | 5:02 pm, February 6th, 2017

You must do so very slowly Vanessa to avoid withdrawal symptoms and with such a long history you may find it difficult to come off altogether. We suggest you stay on them but at a much reduced dose and balance them with bioidentical progesterone from Serenity.

Vanessa | 10:28 pm, February 2nd, 2017

I want to wean myself off evorel 50 been on over 20 years no ovaries and had hysterectomy will it be easy

Lynette DiBiasi | 6:40 pm, January 20th, 2017

I have been on .625 prempro for a few years now, I have steadily gained weight even though I workout 5 days a week. I have been doing some research and believe this is due to the HRT, I would like to stop. Can I cut my pills in 1/2 and take daily how long would I do that before I could stop taking them? OR is it better to take 1 whole pill every 2 days for 2 weeks than every 3 days for 2 weeks?

AnnA Rushton | 9:41 am, January 18th, 2017

With such a short exposure to HRT Sheila you would not expect such severe withdrawal, but it may be that are hormone sensitive in which case you are more likely to react.

Sheila Cameron | 4:39 pm, January 17th, 2017

I was put on HRT tablet form was on them for nine days, stopped them as I got psoriasis on both elbows, I have never had it in my life. I was also getting extreme pmt symptoms. I 52 and the reason I went on the HRT was sex was so painful and my doctor thought it would help. This is my second day without them. I had no sleep at all last night, my elbows are insanely itchy and that is with taking antihistamine s. I have been crying most off the day. Because I was only on them nine days I did not think the withdrawals would be so bad. I have ordered 20-1 cream. I suffer from anxiety and depression and I am so mad with myself for starting the HRT in first place. Surely because I was not on them that long the side effects won’t last too long ? Or does it not work like that ? Thankyou

AnnA Rushton | 12:40 pm, January 10th, 2017

Janette as you are on HRT you must discuss this with your doctor and surgeon as certainly coming off suddenly can cause severe side effects and we advise it needs to be done when supported by bioidentical hormones. Because this is related to your surgery the advice in the article still applies but you do need to discuss this with your doctor as to how long your HRT stays in your system as this is not something we can advise on.

Janette sheerman, | 4:06 pm, January 9th, 2017

I have been recommended for surgerynon my shoulder but my consultant advises me to stop taking my HRT indivini 1 mg for 6 weeks prior to surgery. Advice in this article says to come off them slowly. My surgery is on the 1 March can you advise the best and safest way to come on them. How long does it take to be completely out of your system? Many thanks

HC | 3:54 pm, December 5th, 2016

I had a full hysterectomy at age 31 and have had been on EEMT since. I am 51 now. My doctor has recommended I get off my HRT. I am trying to get off now by taking it every other day for 2 months now I am taking it every 3 days. However, I see my attitude change I am very angry and volatile. Can you recommend me something to take to take the edge off. I am biting everyone’s head off.

AnnA Rushton | 10:06 am, September 18th, 2016

Never a good idea to stop suddenly Donna so follow dr Coope’s advice in the article, and start with serenity. You can switch to 20-1 when off your HRT if you still need some oestrogen.

donna | 9:06 am, September 17th, 2016

have started evorel conti again after six months again ..only been back on them for two months but feel so bloated and have been bleeding occasionally..would like to stop for good but don’t know the best alternative

AnnA Rushton | 7:22 pm, September 5th, 2016

Rita long term HRT, more than 5 years, is not generally in use at the moment and certainly Climaval provides unopposed oestrogen which has been associated with weight gain and other potential risks. The article you refer to by Dr Coope advises on how to do this but if you wish more information please email with these details.

Zita | 1:45 pm, September 4th, 2016

Hi, I’m 48 now, had to have a full hysterectomy when I was 41 and have been on various forms of HRT the time and since consultants and my GP have said it’s advisable to stay on it for 10 years. This last HRT I’ve been on Climaval 2mg for 18 months and a lower dosage of 1mg for about 3 months now, since being on this I have gained a lot of weight, and I really would like to come off HRT all together. I really haven’t felt properly right since my op. Any advise please. Thanks.

AnnA Rushton | 9:51 am, August 20th, 2016

Serine it is progesterone that is needed for osteoporosis and also with your flushes so this article by DR Bond will be helpful:

Nerine | 11:53 am, August 16th, 2016

Hi I had a hysterectomy about 30yrs ago I’m now 70 was on Premarin 625 two a day then one day then onto estradot 25 I have osteoporosis in my back and a few fingers have phlebitis in my legs get very bad headaches take like plus minus 100 syndols a month only thing that doesn’t make me nauses tried going off plasters I get to like 5 days I get flushes and like banging in my head like as if to say put the plaster back and I’m not crazy last year I felt bad and had every test there was and Doctor said I was fine want to stop plaster but would the rest of me just crumble I’m a small person weigh 61kg desperate for advise !!

Janelle | 6:52 pm, August 4th, 2016

You may want to have your cortisol level checked. Do it in the morning and fasting. You should like me and after 3years of agony my cortisol level was low. I think the hysterectomy or the hormone(estrogen) was the cause. Please get this simple blood test. Been losing weight, headaches, stomach pains on and off. Massive fatigue. Cortisol is the hormone that controls your sugar levels(anxiety) blood pressure and inflammation in the body. Good luck and best wishes.

AnnA Rushton | 9:26 am, July 28th, 2016

Ellen this is a very long time to be on HRT as the recommended maximum is now 5-6 years, but a small once weekly dose should not be too difficult to come off when accompanied by using Serenity progesterone cream. Use them together as indicated in the article for a month at the double dose and then email for further advice.

AnnA Rushton | 9:24 am, July 28th, 2016

It is impossible to say Catherine as women vary so much in how they react to the withdrawal and how slowly it was done.

Ellen | 12:53 am, July 27th, 2016

I too have been on estradiol patch for 20 years post hyster. I am on 0.375 mg weekly . I would like to wean off the patch . How I will be feeling physically and emotionally . I am a bit nervous about how I will feel : lack of energy , crabby , tearful , ( menopausal )
Can you please respond . I want to get started ASAP .

Thank you
Ellen .

Catherine Moore | 12:11 am, July 27th, 2016

Started HRT by patch 20yrs ago following hysterectomy. Have reduced dose after consulting with GP over last 5yrs . Was on 25mcgs daily. Stopped about 10days ago. No changes yet. When should I expect flushes etc and for roughly how long

AnnA Rushton | 5:05 pm, July 26th, 2016

Vanessa please speak to your doctor as we cannot advise you on your medication, if you wish to consult Dr Coope directly please see information on his practice here: 

Vanessa Low | 1:45 pm, July 25th, 2016

My menstruation was irregular since 2015. My first day of last period was 10 Jan 2016 and it ended on 20 Jan 2016 (on and off, period did not appear daily). After waiting for 5 months, I went to see a gynae on 1 Jul 2016 and was told that I have started menopause as she had done an ultra sound and confirmed no egg in my ovary. I started taking Livial pills on 1 Jul 2016. On 24 Jul 2016, my period came again (i.e. 6 months from 10 Jan 2016), after I started taking Livial pills. Should I stop taking Livial pills since my period is here again? Does it cause any side effects if I stop taking Livial pills? Thank you!

AnnA Rushton | 9:38 am, June 29th, 2016

Adriana we cannot comment on your medications and supplement as we advise on hormone creams not other products. Please see your doctor about the pain and combination you are taking.

adriana | 9:07 am, June 28th, 2016

I recently started maca and stoped taking femoston2/10
So should i take maca one day then the next day take femoston and slowly stop it that way? I stoped taking femoston for 5days now should i start it again and the slowly ome off it?
Im also just starting to experience some pain in my lower right side just above my hip .. could it be because of the maca?

AnnA Rushton | 2:27 pm, June 5th, 2016

Cindy these are questions best answered by your doctor and as you are in the US you would be best to visit who is a renowned bioidentical doctor and whose site has the resources you need to find someone local to you. We would point out that applying your gel to only one place, your thigh, can limit your absorption. Look at for alternative ways to apply.

Cindy | 1:43 am, June 5th, 2016

I have been taking Divigel 0.1%(0.25 mg) transdermally on my thigh with 100 mg Prometrium for first 12 days of the month, since Spring 2009. I want to get off the Rx merry-go-round….since these are bioidentical and the lowest possible dose, do you tapering off every other day for a couple of weeks, then every two days, couple of weeks, and so on, would be effective? I think 7 years is long enough. I started at 48 and I just turned 55. I’m in the U.S.

Mom had breast cancer twice, phlebitis, stroke & clots are elsewhere in the family history.

I exercise at least 5 days a week, weights twice/week, eat pretty healthfully, don’t drink, don’t smoke, don’t run around on my guy (LOL) – I am fearful of the depression and anxiety aspect returning. I was in pretty bad shape in 2009, until a great doctor put me on the Divigel. What do you think?

AnnA Rushton | 11:23 am, May 1st, 2016

Judy you need to contact whoever prescribed the pellets to you as we can’t comment on other products, but certainly HRT and antibiotics are linked to an increase in anxiety and depression.

Judy | 10:42 pm, April 30th, 2016

I was on bioidentical cream, then switched to pellets. Total about 2 yrs. I have been off several months (last pullet injection Dec 2, 2015). Starting end of March 2016 I’ve had severe anxiety, which I have never had before. I also took antibiotics, which I Googled and found could cause yeast infection in intestines and cause anxiety. I’m not sure if antibiotics or HRT or maybe combination is causing this anxiety. I’ve had it for about a month. It comes and goes, which is weird. Any advice appreciated! Judy

AnnA Rushton | 5:35 pm, April 23rd, 2016

Carol we cannot comment on your regime but it sounds as if you need to speak to whoever prescribed them for you as these symptoms are not usual but a build up of progesterone normally indicates that the application was not sufficiently varied so in fact you receive less hormone as less is absorbed and not enough to deal with symptoms.

Carol | 12:01 am, April 23rd, 2016

Ha! I went on bioidentical HRT creams 4 months after a traumatic menopause at age 47. Then I stopped, because I was losing weight and depressed and crazy anxious. It turned out the progesterone has built up and measured many times higher than normal. I went off it, and my hormones are now lower than post-menopause normal, according to the saliva tests (which I don’t totally trust). I actually get hot flashes if go back to estrogen! But I feel so drained, zero libido, and now sagging and losing muscle drastically. I’m experimeting with wild oat tincture, maca, iodine, exercise, etc. I might try a little DHEA under the tongue. I just want to feel alive again.

AnnA Rushton | 6:55 pm, April 21st, 2016

Janet the withdrawal from the high hormone dosages in HRT can be severe and many women find that 20-1 which is a combination cream with the majority ingredient of progesterone, plus two natural oestrogens is a natural alternative. It would also be helpful to speak to your doctor about the pains in your back and low energy levels to make sure there is no medical cause.

Janet Mullin | 1:13 pm, April 21st, 2016

I came off HRT around six mths ago and since then iv found it very hard to function. I’ve had pain in my stomach and back and generally feel drained, my body has just slowed right down leaving me feeling awful. Can you recommend anything pls.

AnnA Rushton | 9:20 am, April 17th, 2016

Constant headaches must be checked by a doctor Susan to eliminate a number of causes.

Susan | 7:11 pm, April 16th, 2016

Have you had any headaches? I had to stop the Minivelle patch because I had a TIA, mini stroke, two weeks ago. My headaches since have been daily and constant and I cry a lot… I am not one that cries often.

AnnA Rushton | 10:15 am, April 8th, 2016

Coming off slowly is exactly right, but it is normally easier when supported with bioidentical progesterone or progesterone and oestrogens. These withdrawal symptoms are very common so you might want to look at replacing with 20-1 which is a combination cream with the majority ingredient of progesterone, plus two natural oestrogens as you have been on HRT so many years.

Karen Albert | 8:00 pm, April 7th, 2016

I have been taking hormone replacement and have been taking them for about 18 years. My new doctor wants me to stop taking them. I am coming off slowly but have felt a slight headache and a little nauseous. Is this common?

AnnA Rushton | 11:20 am, April 7th, 2016

Mae you need to speak to your doctor if you are concerned but this is probably the withdrawal symptoms from the synthetic hormones in the HRT and will cease when the drug is out of your body. Make sure you start you progesterone at the suggested double dose for the first month and on the following application routine:

Mae wagner | 12:03 pm, April 6th, 2016

Hello and thank you kindly for the time you are taking to answer our questions.
I am 64 and just started taking hormones placement tablets one month ago because my Estrogen and progesterone was low and I was having sleeping problems but after I started taking them I had a change of heart and decided to take the natural route in stead. and 6 days ago I just stop taking them. But now I am experiencing very light blood only as I wipe after urine sometimes, since I have been off them.
My question is since I have been on them for such a short time will these symptoms go away While I am in changing over to natural progesterone and diet? My sleep has come back also since I have been on a natural sleep aid .

AnnA Rushton | 5:40 pm, March 28th, 2016

Angela we are not doctors so not able to advise you so please speak to whoever prescribed these products for you. If you do not have a bioidentical doctor then you may wish to look at this link as Dr Tony Coope is a private GP who offers both personal and email consultations.

Angela | 5:20 pm, March 27th, 2016

Good morning,
I am 47 and perimenopausal. I have been using “natural” estriol and progesterone creams to a largely successful extent until a bout of yeast infections (overconsumption of estriol) had me make a very unwise decision – I quit cold turkey. This bad move caused a fantastic cascade of symptoms that I have been trying to correct since November. Presuming my own ovulation has been shut down from hormone use, I am trying to stimulate its return. I assumed removal of hormones would start the negative feedback loop on its own, but am so itchy and raw that I have gone back to using scant dosage of creams mentioned prior (2 months) but trying to stay under my body’s requirements. Am I on the right track? Any advice would be appreciated.

Wende kendall | 8:13 am, March 18th, 2016

At 38 i had sub-total hysterectomy, leaving just cervix.on hrt from that moment! 2months ago suffering with nightmare day/night allday hot& cold sweats led me to my g.p. as i was already on highest hrt dosage she swapped me there and then onto livial 2.5mg. Took for 7weeks with no improvements , infact i my stomach bloated that i looked 6months pregnant and i gained 10 1bs !!! Shocked or what ! Decided to come off them as was going on holiday and did want to fit into new holiday clothes .Alas that didnt happen i am now over a stone heavier , have had spots of bleeding daily , period pains ( like i sufferd 16 years ago !!!) Feeling lower than low . Await apt at womans hospital 4 weeks away. I am in a state and feel suicidal. Anyone else going through what i am. By the way i am 54 yrs old and feeling it since a few months ago.

AnnA Rushton | 4:02 pm, March 17th, 2016

Linda 20-1 is a bioidentical natural HRT replacement to help your symptoms. Certainly most doctors are not prescribing HRT longer than 5-6 years now because of the associated risks.

Linda Whitfield | 3:58 am, March 16th, 2016

I have been on HRT for over 20yrs… I had a hysterectomy when I was 23 due to cyst and tumors. @ that time I thought I had a complete hysterectomy but my obgyn left my left ovary….well that had to be removed because my Ca125 was very high and I had protentious cancer cells so my Oncologist stopped my HRT and I am going crazy….hot flashes all over again…l am 66 yrs!!! Horrible…any suggestions will help…

AnnA Rushton | 6:33 pm, March 5th, 2016

Marie it is impossible to say as all women are different, but this is why it is important never to stop HRT immediately but gradually wean off with support. For specific drug information please speak to your doctor or pharmacist.

Marie | 5:40 am, March 5th, 2016

How long do withdrawal symptoms from livial last.what are the symptoms of withdrawal.
Kind regards

AnnA Rushton | 6:13 pm, February 21st, 2016

Any oestrogen with a breast cancer history does need to be opposed with progesterone Sheena and the current guidelines recommend no longer than 5 years on HRT. We suggest you start rebalancing with Serenity which is known to be beneficial for breast cancer and safe to use – this article will be helpful:

Sheena lett | 12:06 pm, February 21st, 2016

Hi I had breast cancer in 1998 and in 2001 a full hysterectomy which left me feeling dreadful I was desparate for some help so my gynecologist offered me low dose hrt Everol 50 which I’ve been on with no side effects for over ten years! I now have breast cancer back in the same breast after 17 years I have taken the patch straight off and dreading the effects have I done the right thing

AnnA Rushton | 3:20 pm, January 25th, 2016

Unfortunately Judy unopposed oestrogen does have a number of side effects, particularly when used long term. However although hot flushes and sweats are helped by progesterone, numbness in the toes needs to be investigated by your doctor and you may find this article helpful:

Judy M. | 12:27 am, January 24th, 2016

I was on estrogen after having a complete hysterectomy for almost 30 years. I was on the o.3 until I had breast cancer 2 years ago and then went off the premarin cold turkey. I started having achy bones and my toes got numb shortly afterwards. I also have bad hot flashes and night sweats still. I wondered if the achy bones and numb toes are a side effect from going off the estrogen?

AnnA Rushton | 5:17 pm, December 28th, 2015

Tracy we can’t comment on how long you need to be on your medication, you need to discuss it with your doctor. With bioidentical hormones women stay on them for only as they are needed to control symptoms but coming off HRT can bring on severe withdrawal symptoms. You could balance your oestrogen patches with Serenity as progesterone helps offset any potential oestrogen dominance and protect your heart and your bones from osteoporosis.

Tracy D | 11:14 am, December 28th, 2015

Hi…. I have been on Estradot patches since June 2012, following my total hysterectomy, in April 2012. (Was 37, now 40)
I get on fine with them, but am just wondering how long I need to be ‘on them’ as a whole?… I can’t remember what I was told back then, as I was grieving my fertility,( not having any children before hand) really was dealing with alot.
Just wanted advice really as to how long u should be on them for? Any pointers here would be great, thank you.

AnnA Rushton | 6:35 pm, December 24th, 2015

Linda we are very sorry to hear this and you are experiencing withdrawal symptoms from the oestrogen patches and unfortunately as your levels drop there is no knowing how long it can take for your system to restabilise. Please speak to your doctor about this as they should be able to advise you. When you are able to start with progesterone cream again then start on the double dose for at least the first month to get your levels up again.

Linda.Formica | 4:11 am, December 23rd, 2015

I’ve been on Minnevelle patches 0.5 and progesterone for about 18 month. I’m having knee revision surgery in 2 weeks and at my pre-surgery appointment my doctor told me to stop taking both immediately, so I did. Now, a few days later I have very severe muscle cramps in my knees, legs, feet, hands and toes. I’ve also been VERY irritable. I didn’t give any of this a thought when my ortho dr told me to stop. Can you tell me how long to expect these cramps? Also have light bleeding but I expected that….. I am 60 tomorrow! Help! Is there anything I can do?

Elaine Wright | 7:08 pm, December 17th, 2015

Thanks you for your advice. Can you advise me where to get it from and how long to use it for? If I do nothing am I likely to have another episode like this week? My night sweats and hot flushes are starting to return.

AnnA Rushton | 5:12 pm, December 17th, 2015

Elaine you are having withdrawal symptoms from the high doses of hormone in HRT which is why we advise women coming to off to support with bioidentical hormones as slowly as they can. In your case as you have been stopped immediately, you would be best to use a combination cream such as 20-1 which is a bioidentical form of natural HRT and has no side effects or withdrawal symptoms.

Elaine Wright | 2:11 pm, December 17th, 2015

I have been on the Femseven hrt patches for 18 months but just over a week ago I was advised to stop immediately due to a massive unexpected bleed in mine and as I need surgery to remove fibroids. However on Tuesday I stared with a headache and within 45 minutes I felt like I’d been hit by a train. My whole body ached like I’d got the flu, the pain in my shoulder, neck and hips was unbearable. I was also very cold and shaky but then about 3 hours later I had a hot flush felt sick faint. I started taking ibuprofen and a cold and flu remedy but wondered if this could be withdrawal symptoms from my hrt? If it is is it likely to happen again. Symptoms lasted about 24hrs. Is there anything I can do?

AnnA Rushton | 10:47 am, December 12th, 2015

Tricia we cannot comment on synthetic hormones so please see your GP as it will depend on the type and severity of the bleeding as to whether this is normal.

Tricia Kemish | 11:30 am, December 11th, 2015

I’ve stopped taking Prempak-C 0.625mg HRT tablets. I’ve started a period. Is this normal? A quick answer would be appreciated. Thank you. Take care

AnnA Rushton | 11:27 am, December 8th, 2015

It is always best to come off HRT slowly to avoid withdrawal symptoms and to supplement with bioidentical hormones. As you have been on it so long, you would be best with a combination cream such as 20-1 to replace both progesterone and oestrogen as you need both hormones when off HRT.

Amy | 3:39 pm, December 7th, 2015

I have been on HRT for 19 years following a total hysterectomy. I started slowly weaning myself off it. Today is the first day without any. I am having a lot of cramps and I don’t know if it is from stopping the HRT or if there is another problem. Also, Should I be taking or using something else in it’s place. My sister takes estroven over the counter. Any suggestions?

AnnA Rushton | 4:26 pm, December 3rd, 2015

You may be producing your own oestrogen from the fat cells of the abdomen, hips and thighs but no your hormones don’t reawaken post menopause so certainly won’t be producing progesterone. For osteoporosis progesterone is normally suggested unless you are very slim, in which you won’t be producing oestrogen and would need 20-1 a combined cream. Your dosage is quite high in oestrogen so we recommend you speak to whoever has been prescribing them for you and you may find this article by Dr Shirley Bond helpful:

Rose | 1:26 am, December 3rd, 2015

I am 70 and have been experimenting with taking low dose Bhrt since 2/2015 at 1/4 -1/2 the amount usually prescribed for osteoporosis support (tri-estrogen at between .65-1.00 mg/ml with progesterone between 10-15 mg). Since I began treatment I have noticed that my knee joints and lower back are often painful when exercising or walking several miles. This did not happen before taking the Bhrt.. I have experimented with stopping twice but have worried about osteoporosis so continued again. The first time I stopped for a few months I felt great and the pain stopped, but recently I tried stopping again but the pain increased. I am concerned that my own levels of hormones have decreased even more since taking the Bhrt. Is this possible. If I slowly decrease even the smallish amount I am taking, is it possible for my own hormones, low though they may be, to ‘awaken’ again? I

AnnA Rushton | 11:23 am, October 29th, 2015

You need to email Tracy as bioidentical hormones used with Mirena are not always suitable.
This article may help:

tracy lane | 2:39 am, October 29th, 2015

hi,ive been on climaval for just over a month now,not liking it to much,i have the mirena coil in too.ive decided im going to come off it by taking it every other day,i take 1mg per day,advice needed on what supplement to take to help.thanks.

AnnA Rushton | 8:53 am, October 15th, 2015

Never a good idea to stop suddenly Joann as you will get withdrawal symptoms. As the article suggests combine using Serenity with your Premarin as you cut it down and you can then switch to 20-1 if you still need some oestrogen.

Joann | 2:11 am, October 15th, 2015

Iam 76 yrs old,had a hysterectomy at age 37.I take premarin 0.9mg per day.I was hyperthyroid but had radio active treatment.Now Iam Hypo.but the endo wants me off of Premarin because it is interfereing with my blood results.can I just stop completely or do I need to wean off?

AnnA Rushton | 5:48 pm, October 14th, 2015

Ann you would be best with a progesterone cream as that is the ‘starter’ for other hormones such as testosterone and a pharmacy should be able to sell you this over the counter.

AnnA Rushton | 3:10 pm, October 6th, 2015

A combined cream such as 20-1 is often better for joints Jan but do talk to either a chiropractor, physio or your doctor to rule out any physical problem.

jan | 6:42 pm, October 5th, 2015

i hav come off hrt (kliofem) five months ago and a few weeks i have had severe pain in my knee joints. I am normally fit and do 4 runs per week, now i cant do any running and find it painful tl walk, i am taking cod liver oil and glucosomine. Any advice plse……xxx

AnnA Rushton | 9:08 am, October 1st, 2015

The recommended guidelines for HRT is now no longer than 5 years due to the increased risks of heart disease, stroke and breast cancer Cheryl and you may find a combination cream of both progesterone and oestrogen such as 20-1 would be helpful for your symptoms. Stress always plays a part in hormone balance so this article may be helpful:’t-underestimate-the-effect-of-stress-on-your-hormonal-symptoms/

Cheryl battaglia | 11:49 pm, September 28th, 2015

I’ve been on HRT patch for 22 years decided it was time to come off it I’m 51, I’ve been taking troche compound HRT now for 2 months.
I recently which hasn’t helped went through a hit of stress as my marriage broke down I got a bad flu then I had appendicitis and then gastro so my poor body isn’t going well. I have been on antidepressants for a few years to help but I’m still not feeling too flash, anxious and panicky and considering going back on my patch!! But will it make me feel better maybe it’s just the stress I’m just not sure what to do any help please

Ann | 11:14 pm, September 23rd, 2015

I had a histormecty at the age of 29 for endermodos they put me on parmeronharmones then the Dr said I’ve become bipolar so more meds well they had me up to from a healthy women to a crazy woman up to 16 different meds I’ve got so mush worse an all the Dr want to do is add more meds .I’ve Finley cut most meds back on my own told the Dr all they wanted was my ins and call me crazy but still on harmonie and thyroid meds I went had to pay a lot of money to get my blood work done to find my body has no tesestrone at all I can’t stand to be touched not even the thought of it I only want to sleep I can’t loss weight and I did go a weight control Dr but the meds made me worse .to describe how I feel IS I FEEL LIKE A DEAD PERSON WALKING IN SPACE I CRY ALL THE TIME I DO LIKE BEING AROUND ANYONE OR DOING ANYTHING I USED TO HAVE THE CLEANEST HOUSE AND IN ORDER NOW JIST THROUGH IT IN the FLOOR kick it out of the way I hate my life and how I’ve become I was once a happy positive person people loved to be around .I’m at the end of my rope I’ve tried to get help but wellness centers don’t take ins I’m on disability only they want thousands of dollars to start and go back by weekly basis.why is it that no one care about the real person inside .PLEASE CAN YOU HELP ME I WAS TOLD THE PERMON HARMEON IS THE WORSE

AnnA Rushton | 3:10 pm, September 2nd, 2015

Unfortunately Debbie your hormones crashed from the very high levels in the HRT when you stopped, but bioidentical hormones do not have these side effects or withdrawal symptoms. You may find this helpful:

Debbie Elias | 1:13 pm, September 2nd, 2015

I’ve been taking Livial nearly 11 months,due to a total hystrecomi, felt really good so I came off tablets, it’s been 1 month and I feel like I’m falling apart, aches and pains , arms legs, tummy, lower back and breast, I also have cysts in my breast , gone back on tablets , it’s been nearly 2 weeks, feeling really yuk !!

AnnA Rushton | 4:47 pm, August 9th, 2015

Heather with such a very long time on HRT you must discuss this with your doctor as withdrawal symptoms could be severe. Start first as the article suggests and add progesterone at the same time as you are cutting down on your patches. When you are off the patches you can then switch to a combination cream if you still need some oestrogen.

Heather Nel | 4:10 am, August 9th, 2015

Been on Estradot 50 patches for 20years after complete historectomy. How do I proceed to go off. Facial skin very dry and itchy scalp with hair thinning. Is this a side affect of HRT ?

AnnA Rushton | 11:40 am, August 4th, 2015

GP’s can prescribe on the NHS but it is entirely at the discretion of the practice or you can obtain a private prescription – however the simplest option – and least expensive – is to order directly. Two private GP’s who do prescribe – Dr Shirely Bond and Dr Tony Coope – can be found at this link:

Jill | 2:32 pm, August 3rd, 2015

Is the cream available UK either on prescription or privately. Many thanks got your prompt reply Ann.

AnnA Rushton | 11:40 am, August 3rd, 2015

20-1 is a combination cream containing both progesterone and oestrogen Jill and is a bioidentical HRT replacement. You can use it as you cut down your HRT and then afterwards to help with your symptoms. Bioidentical hormones do not have side effects or withdrawal symptoms so can safely used alongside your HRT.

Jill | 4:43 pm, August 2nd, 2015

I have been on HRT for 25 years following an oopherectomy . I tried to come off cold turkey about four years ago but flushes etc were awful. I went back on to Indivina, lowest dose , but now my GP would like me to come off. I have had Polymyalgia Rheumatica for three years and am not sure I could cope with anything else. The steroid side effects are bad enough, she has told me to think about it and maybe start taking it alternate days. I am 64 . What is the 20-1 that keeps getting mentioned. I would be very grateful for any help.

AnnA Rushton | 6:55 pm, July 28th, 2015

Jane unfortunately, as the article indicates, it is never good to come off HRT too suddenly and without the support of bioidentical hormones during the transition as withdrawal symptoms can be very severe. If you still have your HRT we would suggest you go back to every other day until you have some 20-1 to use alongside it and then you can gradually taper it off.

Jane | 8:24 am, July 28th, 2015

I had a total hysterectomy at the age of 34, I am now 51 and have been on HRT since my hysterectomy, my GP advised I come off HRT, for a couple of weeks I reduced my HRT, taking it every other day, I then decided to stop all together, I am now feeling absolutely horrendous, hot and cold flushes constantly throughout the day and night and severe headaches and migraines, also constantly throughout the day, I feel like my head and eyes are going to burst, I cant sleep and I am exhausted … I cant take much more of this … please, please help me

AnnA Rushton | 9:54 am, July 27th, 2015

It is always best to come off HRT slowly Veronica so you may want to consider using progesterone to balance the oestrogen of the implants now and that will help with both your current symptoms and support you if you do decide to stop HRT.

Veronica Cooksey | 5:30 pm, July 26th, 2015

reading these comments has helped me to realise I’m not alone. I have been taking HRT for 25 years but for the last 18 months I decided to come off them and try another alternative. Ive tried others in the past but because I was really young, they didn’t work. So now I decided to try Evorel 50 which had really bad side effects; numbness down one side of face and very weird head sensations which were awful.
Now I’m back on Estrodial Implants which I finally feel myself so for me I’d rather have a quality of life then not being able to go out feel depressed, moody, irritable, nauseous and dizzy most of the time. I will and some stage come off all together, but right now I’ve got a life to lead.

AnnA Rushton | 3:34 pm, July 16th, 2015

Irene after so long on HRT it is difficult to come off easily but we suggest you don’t cut down until you can support yourself with a bioidentical cream and 20-1 would be best for this purpose. Use it alongside your HRT for a week or so and then cut down the HRT very gradually and this will help minimise the withdrawal symptoms, but having been on it as long as you have there may still be some.

Irene B. Lomayani | 2:49 pm, July 16th, 2015

In 1996 I had total removal of the uterus, Fallopian tubes and overies due to severe fibroids. My doctor put me on HRT to avoid premature menopause.
It has been 19 years now and I am getting to 70 years old.

After 5 years, I wanted to quit due to scaring negative literature. My doctor encouraged me to continue but put me on Premarin 0.3 mg daily,a relatively lower doze.

I have been feeling great. But. I tried to wean myself off by taking the tablets on alternative days. Flushes and sweating were uncomfortable. I have regular medical check ups including mammogram, pep smear….an so far all is fine. My breast however, appear fuller. I go to the gym regularly. I take food supplements: calcium, vit C, centrum and Omega 3,6&9.

When and how can I safely quit with less side effects. I live in Africa so the alternative medicines and creams mentioned above are out of reach. Please advise.

AnnA Rushton | 4:40 pm, July 7th, 2015

Dolores your sister should contact whoever she obtained the hormones from to ask their advice, as products vary in their strength and intensity. Generally there are no withdrawal symptoms on bioidentical cream formulations but she may be on a higher dose and if she has not felt benefit being on them or off them then she needs to see her doctor to investigate exactly what the problem is.

Dolores Lombardi | 9:39 pm, July 6th, 2015

My sister is on bio-dentical hormone replacement since Sept. 2004. She does 4 pumps per day. She decided to ween herself off of them taking 2 or 3 pumps now she not taken any. She doesn’t feel well but I don’t know if it’s the hormones because she may have depression. are there any side effects by stopping it. She didn’t feel good on them & don’t feel good off them. What can she do?

AnnA Rushton | 7:55 pm, June 25th, 2015

Loretta unfortunately you have been on HRT so long it can take quite a while for your body to adjust to the crash of the hormones, particularly if it is stopped suddenly. If you want to support your withdrawal you could use bioidentical progesterone cream to help rebalance your hormones and get symptoms under control.

Loretta Kent | 7:02 am, June 25th, 2015

I am 70 year old and have been on HRT for 38 years. Finally 2years ago my doctor cut my Estradiol down to 0.5 and the Medroxypr to 2.5. One week ago they discovered a blood clot in my leg and I stopped cold turkey. I play tennis and swim daily. I’m shaky, weak, very tired and have a head ache. How long before this passes?

AnnA Rushton | 8:52 am, June 19th, 2015

Unfortunately this is what happens when you stop directly and your symptoms relate to your body trying to adjust to the rapid drop in the high level of synthetic hormones your body had become used to on HRT. We would suggest you need a combination cream such as 20-1 to restore naturally those hormone levels and protect your bones from osteoporosis.

Diane | 11:20 am, June 18th, 2015

I have been on Hrt for 26 years, after a two week bleed my doctor has taken me off it cold turkey. After ten days I have
Strange side effects, heavy eyelids,
Aching arms, and occasional hot flushes,no mood swings very vague and forgetful, I am wondering how long it take before I have no estogen in my body.
Will my bones deteriorate? I am 66 and look and feel early fifties. Also my hair is suddenly unruly and feels wired.
Has anyone else had the same symptoms?

AnnA Rushton | 9:44 am, June 18th, 2015

As the article indicates Beverley it is never a good idea to come off HRT suddenly as you go into immediate menopause and there is no knowing how long that will last. Leave the patch on until you can support it with progesterone (Serenity) then reduce the dosage gradually and monitor your symptoms. If you still need oestrogen when off the patch you can switch to a combination cream (20-1).

beverley hilder | 1:25 pm, June 17th, 2015

Hi I had a hysterectomy and ovaries removed at the age of 38 and tried several types of hrt. and finally settled on Evorel first taking 50 and now I take 25 changing the patch twice a week. I am 58year old and tried a few times without success. my GP mentioned again I have been on it a long time and suggested I try stop taking it he said you will go straight through the menopause which shouldn’t last two long them that will be it i will be over it. well this is my third week and I am not sleeping really bad heads and absolutely wet through on and of and feeling terrible. I have just put a patch back on and want to ask would I be better leaving the patch on longer or chopping it in half each patch contains 1.6mg Estradiol that Absorption rate 25 micrograms of Estiradiol in 24hrs please advice thanks

AnnA Rushton | 8:12 am, June 15th, 2015

Yes weight gain at menopause is normal Lynnie but will depend on the degree of oestrogen dominance you have and coming off HRT suddenly can increase symptoms. This article will help:

Lynnie | 6:03 pm, June 14th, 2015

I had been taking hrt tablets for about 2yrs I decided to stop taking them as it only prevents the symptoms and you would have to go through it eventually but since I stopped taking them I’ve put on over a stone is this normal I just stopped I did not wean myself off them

AnnA Rushton | 1:08 pm, May 26th, 2015

Tonda we cannot comment on how long your flashes while on HRT will take as it varies in individual women and it is impossible to say as the high levels of hormones in HRT mask the symptoms.

Tonda | 3:34 pm, May 25th, 2015

I tried going off hrt and started having hot flashes so doctor said I could go back on how long will it take for the hot flashes to go away

Sarah L | 11:05 am, May 25th, 2015

I am coming to the last 4 days of the second month of Elleste Duet 1mg and I have put on a rapid half a stone especially round the tops of my legs and middle. So much so that stretch marks have appeared! I now want to stop. Can I just stop at the end of the packet as I’ve only been on it for 2 months? Is the weight gain due to there being too much oestrogen for me? More than my body requires? Is it worth me trying another type of hrt or will they all do the same thing to me?

AnnA Rushton | 4:03 pm, May 11th, 2015

Romy we cannot comment on your drug as we are not medical staff, but it is an oral form of progesterone that passes through the liver and has to be given in much higher doses to compensate for this. Cream application has much lower doses and no reported side effects but if you are having weight gain and enlarged breasts that normally indicates some oestrogen dominance so we suggest you discuss this with your doctor as you may be over sensitising your oestrogen receptors.

Romy | 5:59 am, May 11th, 2015

I am 50 with regular periods. Have been using pill prometrium for 7 years, added cream (sleep poor, sweats) in jan 2015 with a progesterone level of 6 just tested now at 142. No sweats. Sleep not 100% but ok. Some weight gain, breasts larger.

Not sure what to think….thoughts

AnnA Rushton | 10:12 am, April 29th, 2015

Dee you need to speak to your doctor as implants are very different in nature to cream forms of bioidentical hormones. There are no side effects associated with transdermal progesterone creams, though there are with synthetic progestins, and they are acknowledged as the best way to deliver hormones safely. This article may be helpful:

Dee | 3:24 am, April 29th, 2015

I began the bio-identical pellet HRT in January, 2015…..began having rages within 5 days. Dr. took me off of the Thyroid Synergy and Adren-All that they prescribed at the same time, stating that these two meds were the cause of the rages. The rages subsided a little bit but they kept me on the progesterone and DHEA….after 3 months, I had my second pellet put in just 10 days ago and the rages are worse now than ever. I have been reading about some of the side effects of progesterone and I keep continuously keep reading comments about how women are having these serious rages. I cannot stay on this pellet or continue with the progesterone because I’m fearful for my life or hurting someone, the rages get that bad. I’ll take the hot flashes and night sweats any day over the horrible rages.

AnnA Rushton | 10:50 am, April 12th, 2015

Niran this is a question for the doctor who prescribed Elleste for you as we do not have information on HRT.

niran | 8:16 pm, April 11th, 2015

I started elest duet2mg 3 weeks ago I got urine infection stomache pain today I started spotting can I stop the tablet

AnnA Rushton | 1:21 pm, April 8th, 2015

It is down to the plunging hormone levels that happen when you come off HRT which is why we recommend slow reduction and supplementing with bioidentical hormones. As you already off it, you would be best Dee to use a combined progesterone and oestrogen cream such as 20-1 to build up your levels to deal with your symptoms and certainly headaches are related to oestrogen so the sudden withdrawal can have triggered them.

Dee | 9:54 am, April 8th, 2015

Hi there I’ve been on HRT for 5yrs and Dr Recomended to stay on only five years, I took my last pill 6days ago, since coming off I’ve felt Tired, lack of energy, and severe migraine headaches in the evening, my eyes are very red n soar, I’ve had a slight numbness in my hands n fingers. But I’m having to wear dark glasses at night as the light is unbearable, I’m wondering if the bad headaches are part of the lack of HRT as I’ve read several comments and no one mentions headaches just hot flushes please advise if this is a symptom

AnnA Rushton | 1:09 pm, April 2nd, 2015

As Dr Coope states in the article Pamela with oestrogen only HRT you cut it down over two months once you have started using Serenity at the same time. It is very important you go slowly to reduce your withdrawal symptoms but women are different so you will have to experiment. You can just cut a small amount from the patch in the first instance – say a quarter or less and do that for two weeks, then reduce so you have perhaps half the patch for two weeks. If symptoms are manageable cut down a further quarter for two weeks then stop. If symptoms are severe when cutting down stay on that amount longer and just go at the pace your body wants to.

Pamela Herne | 10:09 am, April 2nd, 2015

Hello its me again i sent a comment 10 mins ago and forgot to say the patches i am on are Estaderm MX 50 i asked you how i can come off these slowly.
thank you.

Pamela Herne | 9:55 am, April 2nd, 2015

I have been on HRT patches for 30yrs i have moved and my new doctor wants to take me off the hrt how do i come off patches slowly.I am 78yrs old.Ihave tried several times but get severe hot flushes.

AnnA Rushton | 11:53 am, March 31st, 2015

Susan you need progesterone and oestrogen for your bones, but women who have come off HRT often do better with 20-1 as a combined cream gives you a natural bioidentical form of HRT. Progesterone will help with the foggy brain too – but see this article for help with osteoporosis.

Susan Daugherty | 5:59 am, March 31st, 2015

Wish I had seen this post before stopping my estradiol 3 weeks ago. I’ve had hot flashes, insomnia, temper flare ups, etc., but I think it is calming down some. Now what? Osteoporosis runs in the family soe bone deterioration worries me. I’ve also experienced “foggy brain” and that is really frustrating! Suggestions?

Mrs Margaret Hosie | 7:17 pm, March 3rd, 2015

Been taking Livial HRT since having a hysterectomy at the age of 38. No problems whatsoever, I felt remarkably well and looked ten years younger. However after being advised to gradually reduce them over two years, then finally come off them completely, I have experienced terrible horrible hot flushes and the nasty headaches and generally feeling nausea and deeply depressed. I am age 69. Dr. has put me back on the Livial.” Praise the Lord”. I prefer a high quality existence rather than all those horrible embarrassing symptoms and having to have two showers every day, sometimes three.

AnnA Rushton | 1:32 pm, February 26th, 2015

You can get bleeding as hormones rebalance as it often the shedding of endometrial lining but such a prolonged bleed should be investigated by your Doctor Angela.

Angela | 1:24 am, February 26th, 2015

I was on bio-idential hormones for only 3 months. I decided to stop suddenly without consultation. I am now experiencing a prolonged menstral bleeding almost 3 weeks. I am not sure if my body will fix itself or if there is anything I should do.

AnnA Rushton | 11:27 am, February 23rd, 2015

Cheryl definitely use Serenity while coming off HRT and follow the guidelines in the article.

AnnA Rushton | 11:21 am, February 23rd, 2015

Unfortunately Marlene it will depend on the severity of your symptoms as to how you are affected when coming off HRT.

Cheryl | 7:19 pm, February 13th, 2015

I have been on hrt for 14 years due to going through the menopause at 40. My gp tells me the early years don’t count as hrt is only replacing the hormones my body would make naturally. I feel it’s maybe time to try and wean myself off it, my gp suggested when I was ready, start taking it every other day. You advise to keep taking the progesterone whilst I do this, when should I stop taking this?

AnnA Rushton | 11:11 am, January 28th, 2015

Unfortunately Marlene it does depend on the level of oestrogen dominance as to how you react to coming off HRT and with 10 years of unopposed oestrogen that means you are more likely to have a severe reaction.

Marlene | 1:49 pm, January 26th, 2015

Hi there. I have been on activelle which I take every day for 10 years now. I did try to quit a few times but had so much side effects I went back on it. Now my doctor wants me to stop taking it. The thing is there is hardly any info available about how to taper of this which annoys me a lot. I tried taking no pil on wednesday and saturday but got so sick. Now on those 2 days I take a half. (have to cut the pills which is not easy) but I still have hot flashes and lots of cramp even going slowly.Decided to make an appointment not with my own male doctor but with a female one. Is it normal to feel so horrible when reducing so little? thanks.

AnnA Rushton | 5:57 pm, January 20th, 2015

Marcella 5 years is now the maximum recommended time to be on HRT so if you still have symptoms you probably want to consider an alternative. Never a good idea to come off quickly but given the length of time you have been on it you would be better with a combination cream such as 20-1 which is a natural HRT replacement. You would need to use it at the same time as you withdraw from Premarin and would need the double dose for at least the first month.

Marcella | 10:16 pm, January 18th, 2015

I have been on Premarin for 35 years following a complete hysterectomy. I attempted to wean myself off of it a few years ago. Felt like I had the flu along with suicidal thoughts. At the age of 65 Medicare has sent a letter saying they will no longer cover the cost of the Premarin. I am fearful of not taking the Premarin as I don’t think I would survive the withdrawal. At my age, should I still be taking an HRT? Any suggestions? Please help.

AnnA Rushton | 11:38 am, November 9th, 2014

It always advisable to withdraw slowly from HRT due to the very high levels of hormones it contains and certainly that is what is recommended by bioidentical doctors and professionals working with complementary health. Unfortunately many doctors do not always follow this advice and terminate HRT suddenly which accounts for the severity of the symptoms that can follow withdrawal.

AnnA Rushton | 4:57 pm, October 30th, 2014

Many practitioners do advocate using a probiotic as it can certainly improve the gut health.

Joan | 3:02 pm, October 30th, 2014

Thank you for responding. I have had some symptoms, so am going back to 3 clicks a day. Also, I read where sometimes one had gut symptoms, and I am feeling slightly nauseous. Do you suggest a pro-biotic?

AnnA Rushton | 7:39 am, October 29th, 2014

We don’t know this form of HRT Joan but your doctor is correct, there is no time frame, you just reduce gradually until you are symptom free but generally a week at each level would be average.

Joan | 4:05 am, October 29th, 2014

I am weaning off bio-identical hormone cream. I was on 4 “clicks” of the dispenser per day. Doc suggested I do 3 clicks and if symptoms occur go back up for a couple of days, 3 for a couple of days, etc, then when no symptoms use just 3 clicks for a while, if no symptoms keep reducing. However, he gave me no time frame. So far I have had a few hot flashes, but am doing ok. How quickly can I move off? multiple weeks at each level, one week at each level? I am confused how to proceed.

AnnA Rushton | 8:54 am, October 24th, 2014

Amanda slowly is best and so increase your progesterone cream as this is the hormone that helps you sleep. Stay on the dosage of patch you have reduced to until you get your sleep under control and then reduce again.

Amanda | 10:31 pm, October 23rd, 2014

I am weaning off my oestrogen patches slowly, I have been on them for about 10 or more years, I am now having difficulty with getting to sleep at night, is this a side effect !

AnnA Rushton | 5:36 pm, October 3rd, 2014

As Dr Coope’s article explains, coming off HRT suddenly is never a good idea as severe menopausal symptoms such as flushes and sweats usually result. Slow withdrawal and supplemention with bioidentical progesterone is the best route.

Mickey | 11:05 am, October 3rd, 2014

I have been on bio-identical HRT for over a year now. Will be 50 this month. My OB Gyn suggested I was having a hard time with depression prior to it so she was coming at it from that angle.
I want to get off of it due to lack of finances. I read in all the comments that going off cold turkey has severe symptoms what are some of the symptoms to be expected? How does one combat them? Please help

AnnA Rushton | 1:49 pm, September 1st, 2014

Sarah we can’t comment on your doctors recommendations. Certainly 5 years is now the maximum time suggested for women to be on HRT because of the risks but no HRT should be stopped suddenly because of the risk of severe side symptoms on withdrawal. For women with such a long history of HRT use you would be better if you intend coming off HRT to use a combination cream such as 20-1 which has both progesterone and oestrogen.

Sarah Fuchs | 10:12 am, August 31st, 2014

Hi. I am very confused. I had a total hysterectomy when I was 32 years old and was on Premarin for many years. I started taking Livial 9 years ago and I’m now 65. I look 10 years younger and am still sexually active. I go to a specialist once a year to have him check my breasts and I also have a mammograph and ultrasound once a year now. He thinks that I should stop all HRT. My GP doesn’t see why I should come off Livial. I ran out of my pills 4 days ago and am thinking maybe I should stop taking Livial now. I don’t know what to do. Overall I am healthy besides high cholesterol (medicated). I’ve been getting a lot of leg cramps recently – more than a month now. What should I do?

AnnA Rushton | 11:48 pm, August 14th, 2014

When you stop HRT, particulately if done suddenly, then symptoms can be severe and in this case production of oestrogen switches to the fat cells in the abdomen, stomach and thighs.

susan mcpartland | 7:58 pm, August 13th, 2014

Hi i have stopped taking HRT Livial but seem to be gaining lots of weight is this normal ?

AnnA Rushton | 10:01 am, August 13th, 2014

Stopping HRT immediately is never a good idea as you can severe withdrawal. You need to speak to your doctor on how to manage your patches as you are having both oestrogen and synthetic progestins in the coil.

kim | 7:40 am, August 13th, 2014

Hi I’m evorel 50 and two weeks I go I just stopped using the patches no reason just wanted to see if I could go without I’m now wanting to go back after realising I’m better on them my Dr put me on them because before I w as due a period I use to feel like crying my head felt really strange I didn’t feel ill but just couldn’t describe it I just felt rather strange before a period was due but now that j don’t get periods,and have a marina coil fitted as well was just wondering wether I could just start my patches again starting on a new day

carol walls | 1:32 pm, August 10th, 2014

Hi Shirley
I am 62 years old my Dr has taken me off hrt as my blood presser went up.she says i have got to come off it some time.the nurse has been taking my blood presser now with 10mg tablets it is back as it was.
I have been off hrt for one year before
nearly had a break down.could not coupe with anything at gp put me back on it last year but has since left.
I now have a new gp who is very good
but wants me off the hrt because of the risks and my age. she says she will put me back on it when my blood presser goes down.I have to see my gp next week she says I will have to syn a form so she is not to blame if anything happens to me I am going to ask if I can go back on it for a while and then start to reduce them slowly and see if that will work. but I think I am one of those people who will never get rid of the menopause symptons long as I Live?

Julie E | 9:05 pm, July 16th, 2014

I have been on the Minivelle patch for one month, and have gained weight to the point where I am crawling out of my skin. I stopped taking it, and am now just using the vaginal cream. I would rather have hot flashes then feel like the Michelin man. For me, it was not worth it.

AnnA Rushton | 3:50 pm, August 23rd, 2013

You would need to speak to your GP Cindy as Prometrium is a high dose progesterone and although the cream formulas can be stopped immediately we do not know what the withdrawal from a pessary like this would be.

Cindy Maxwell | 6:57 pm, August 22nd, 2013

I am 57 yrs. old. stopped taking estrodiol 2 years ago, but have continued taking 200 mg. of prometrium since then. Can I just stop taking the prometrium “cold turkey” ? They are in gel form so I cannot cut them.

AnnA Rushton | 9:41 am, June 18th, 2013

Mary you can buy 20-1 at

Mary Hughes | 4:08 pm, June 7th, 2013

Hi, can you tell me where I can buy the
20-1 cream .I have come off HRT ,dont want to take pills .
Thank You
Mary Hughes

AnnA Rushton | 1:44 pm, May 4th, 2013

How you age is dependent on many factors and coming off HRT is not likely to be a factor. If you are concerned then a cream such as 20-1 will give you both progesterone and oestrogen and it is oestrogen that increases the rate of cell turnover in the basal layer of the epidermis which makes skin appear plumper.

Romy | 9:50 am, May 4th, 2013

Ive been on hrt tablets for three years,and wish to come off,Dr has advised to take one every other day,and then every two days,until I have weened myself off,I just want to know,will I start looking old,will my face start getting wrinkled,I get told I look young for my age,I know every one is talking about what will happen to the body,but no one is mentioning how you will look,please can anyone give me answers tahnk you

AnnA Rushton | 11:02 am, March 2nd, 2013

Gerri – as your hormones rebalance old stored blood can be released, and the body can hold on to this for some time and can be linked to the degree of oestrogen dominance and how heavy your periods have been. Unless the bleeding is heavy or prolonged there is no cause for concern but if not then please see your doctor.

Gerri | 8:20 pm, March 1st, 2013

I was on the Biohormones (compound). Iwas off of them for weeks, started not feeling well and had spotting so I started taking them again. Have been on them for 3 weeks and now I am spotting. Is this normal?

Carol | 3:11 pm, January 18th, 2013

I reduced my level of HRT by half about six months ago but am experiencing terrible pain in my arms, shoulders and lower bag and legs. How long does this usually go on for?

Linda | 12:26 pm, December 10th, 2012

I was fine on hrt for 13 yrs,dident go on it for menopause,but for bones,as I had polio as a child,the doctor took me off the hrt,I am now a complete wreck ,arms,wrists aching pain,cant turn over in bed ,sleep disorder,which I never suffered before,cant walk far at all without help,not sure if the late effects of polio contribute,or its just comming off the hrt.just need advice on what suppliment to take,doctors do not realise post polio syndrome. linda

sue | 6:32 am, November 13th, 2012

I have been on ellestte. duet 1 mg for 6 months and feel great on it , hot flushes stopped almost right away which was a god send . But my hair has been shedding since i started the tablets now only have half the head of hair i had before i started taking them ,my hair is

all over the house and anywhere i visit

Rigor | 10:40 pm, October 24th, 2012

Ovarian Cyst Surgery-Partial Hysterectomy done?I had a hystorectomy on June 2005 my Gyn rednmmeoced to leave my ovaries so they won’t have to put me on medications so young (I don’t consider myself that young but anyways) after all this I have been having constant pain on my right side is sharp and dull and sometimes I did not know how to describe I went back and behold a ultrasound detected a small cyst on my right ovary.I have an appointment with the Gyn but not soon my question: since I had a hysterectomy I wonder what is going to be their approach about this painful and bothersome little cyst medication? or is this probably a simple surgery in the future? Any one out there with the same experience would be a lot of help )thnks.Those answers helped thnks. I am extending the days on my question maybe a girl out there has also gone by hysterectomy and also had ovaries taken out due to this in all i think my histeria is due to know wheather or not I am going to be proposed another surgery (?)thks

Maham | 4:22 pm, October 24th, 2012

Hi Liz and LindaI’m concerned about your avdcie Linda re livial. I had endometriosis and had six injections of decapeptyl before a hysterectomy on 3 oct. Almost as soon as my injections kicked in I had menopausal symptoms, so was given livial. Livial worked really well and did not bring back the endo. My consultant told me that because of the hormone ( synthetic) in the livial, it wouldn’t act like oestrogen and so wouldn’t affect the endo. The injections worked very well but had to have the hyst because the injections couldn’t be done indefinitely. Compared with the quality of life before livial, I would definitely give it a try. It might not work for everyone, but don’t make a decision based on worry about endo as I was assured there’d be no problem. Hope you get something sorted out soonHazel

HS | 5:20 pm, October 7th, 2012

i am also in a dilemna..i take them feel better, when i try to go off them , i get angry, hot flushes, and depressed! and if i go off them..and perhaps i could live a longer life? does one choose between the quality of life .or longer life? hmmm..that is the question for each of us eh!

Julie Larratt | 11:57 am, October 2nd, 2012

Hi I have been taking HRT for about 10 yrs as I was post menopausal at the age of 40. I feel really well on HRT but the Dr as advised i come off it as the risk increase after 10 yrs. I have no breast cancer in the family of DVT . I have started to take a pill every other day but found the first day without it I have flushes during the night I’m not sure if I’m doing the right thing when i feel so well taking it.

dawn | 10:31 pm, March 17th, 2011

my docter as took me of hrt wiv out cuttin me down i ave been on them for 16yrs and now gettin side effects wot can i do 4 this or sould i go back 2 my docter.

rosemary | 9:04 pm, January 14th, 2011

I have been taking bio-identical HR creams for 18 months but my uterine lining has become thick and my dr. wants me to come off them. She said to cut down the number of days I use it each week til I am down to once a week (creams) and then stop taking them.and she prescribed prometrium starting now for 3 months for me to reduce the lining thickness and the risk of uterine cancer, What is your opinion of the use of prometrium in this case and how to come off the bio-identical hormones.

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